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Fact Sheet: Syphilis

Before the advent of penicillin, syphilis was an incurable infection that affected many people including well known historical figures such as Henry VIII. Syphilis was frequently passed from mother to child, and congenital syphilis was the terrible secret underlying the action of Ibsen’s play, Ghosts. Syphilis is now easily treatable in its early stages. Infection rates are high in some parts of the country, and there is currently a local increase of syphilis among men who have sex with men.

WHAT IS IT?

Syphilis is caused by a bacteria (Treponema pallidum) that is curable with antibiotics. If not treated early, however, syphilis can cause serious problems.

TRANSMISSION

Syphilis is spread during sexual exposure to an infected person. It can also be transmitted from an infected mother to her child during pregnancy (congenital syphilis). Syphilis is a disease having different "stages" and because the symptoms that occur soon after infection go away without treatment, people may mistakenly think they are cured or have recovered when, in fact, they are infected and can pass the infection to their sexual partners.

SYMPTOMS

The first stage of infection is known as primary syphilis. The first symptom of infection is an often painless sore (chancre) that appears 10 – 90 days (average 3 weeks) after contact with an infected person. Most often the chancre appears on the genitals, but may appear in the anorectal area, the mouth, or other parts of the body if that is the site of infection. These sores look painful, but often they aren’t and go away on their own in 1-5 weeks. Because they are painless, they may go unnoticed if they occur inside the vagina or rectum.

The next stage, secondary syphilis, may begin immediately following the primary stage or up to 10 weeks later. Secondary syphilis is most often characterized by a rash on the palms of the hands and soles of the feet or on the chest or back. Some people may have genital lesions, flu-like symptoms or may have loss of hair during this stage of syphilis. Like primary syphilis, the symptoms of secondary syphilis go away without treatment, but the infection continues to progress.

If syphilis is not diagnosed and treated during the primary or secondary stage, the disease enters an extended period with no symptoms (latent infection). During this period the infection continues to cause damage to the body. Up to one third of untreated persons will develop complications due to syphilis at the end of this latent period (tertiary syphilis.). Complications may include damage to the arteries and/or dementia or blindness. If left untreated syphilis can result in death. The likelihood of transmission decreases during these later stages, but some risk remains.

PREGNANCY

A pregnant woman can pass the infection to her child. A fetus can become infected as early as the 4th month of pregnancy, resulting in stillborn or premature delivery and neo-natal death in 20% of infected infants. Other symptoms and complications of congenital syphilis may include nasal discharge in the first weeks of life, jaundice, anemia, and bone disease. Pregnant women infected with syphilis can be effectively treated with penicillin, usually resulting in a cure for the infant as well. Even so, the infant should be evaluated and given further treatment if necessary.

DIAGNOSIS

Only a health care provider can diagnose syphilis. Diagnostic tests for primary and secondary syphilis include blood tests and tests performed on fluid recovered from open chancres. For some infected persons, e.g. those with latent or late disease, examination of spinal fluid may be performed to determine central nervous system involvement.

TREATMENT

Penicillin is very effective at treating primary and secondary syphilis infection. Latent or tertiary syphilis requires more intensive treatment, but can be cured. Nonetheless, any damage done by the disease is permanent. Sexual contacts of individuals diagnosed with syphilis should be notified, tested and treated as necessary. People can become reinfected with syphilis and must continue to take precautions to prevent repeat infections.

PREVENTION

  • Abstinence from sexual activity is the surest way to avoid acquiring or transmitting syphilis.
  • The next surest way is to limit sexual contact to one uninfected partner who only has sex with you.
  • For those choosing to be sexually active, condoms should be used correctly and consistently to minimize transmission.
  • Avoid sexual contact if suspicious symptoms are present. If you suspect that you have syphilis (or any sexually transmitted disease), seek immediate care at a local STD clinic, hospital, or medical practitioner.
  • Before having sex, talk with your partner(s) about syphilis and other sexually transmitted diseases. Negotiate a risk reduction strategy with them that feels comfortable to both of you. If the STD status for you or your partner is unknown, go together to get screened at a local STD clinic, hospital, or medical practitioner.
  • If you have syphilis (or any sexually transmitted disease), notify all sex partners so that they can also seek and obtain treatment.

In the News:  Health experts - Syphilis rates rising (CNN)


Information courtesy of Seattle and King County Public Health
at (http://www.metrokc.gov/health/)


Return to Sexually Transmitted Disease Page