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Harold N. Adel, MD, MPH
Commissioner
Department of Health |
Andrew
J. Spano
County Executive |
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FOR IMMEDIATE RELEASEDecember 23, 1998
Lyme Disease Vaccine
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FOR MORE INFORMATIONContact
Mary Landrigan
(914) 637-4715 |
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The Westchester County Department
of Health today announced the FDA approval of the first vaccine for Lyme disease. The new
vaccine, LYMErix, is approved for use in people 15 to 70 years of age who live or work in
grassy or wooded areas where infected ticks are present. "The vaccine offers
Westchester residents another defense against Lyme disease and will be available in
January," stated Dr. Harold N. Adel, Westchester County Health Commissioner.
"Residents considering the vaccine should consult with their physicians."
For maximum protection, three injections of the vaccine must be taken over a one year
period. The injections are given at 0,1 and 12 months. After three shots the vaccine was
shown to be 78% effective, after two shots 50% effective.
"Although this is a significant breakthrough, residents should not stop taking the
standard precautions against tickborne diseases, such as wearing protective clothing and
doing tick checks," Dr. Adel added. "The vaccine is not 100% effective and
offers no protection against other tickborne diseases such as ehrlichiosis."
LYMErix contains a genetically engineered protein from an outer surface protein of
Borrelia burgdorferi, the spiral shaped bacterium that is responsible for Lyme disease.
The surface protein, called OspA, stimulates antibodies that appear to disable the
bacterium's ability to infect the individual.
SmithKline Beecham, the manufacturer of the vaccine, is studying whether booster shots
will be necessary. The company is also conducting a clinical trial on whether the vaccine
is safe for children under 15 years of age. The vaccine is not recommended for use yet in children, pregnant
women, those already with chronic Lyme disease, and those already with chronic arthritis.
The vaccine also may interfere with testing for the diagnosis of Lyme disease.
Lyme disease is passed on to people through the bite of an infected deer tick. The most
common symptom is an expanding red rash, often at the site of the tick bite. The rash
usually appears three to 30 days after the bite and may last for weeks. Other symptoms may
include fever, sore throat, fatigue, sleeping difficulties, stiff neck, joint and muscle
pain, swollen glands and dizziness.
Ehrlichiosis is also spread through the bite of an infected deer tick. Symptoms of
ehrlichiosis can include fever, headache, chills, malaise, muscle and joint pain, and
nausea and vomiting. Acute weight loss, low platelet count, and low white blood cell count
can also occur.
For more information on the Lyme disease vaccine,
call the Westchester County Department of Health at (914) 813-5000. Information for the
general public and physicians will be available shortly at the Westchester County
Department of Health website www.co.westchester.ny.us/health.
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