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Harold N. Adel, MD, MPH
Commissioner
Department of Health

Andrew J. Spano
County Executive



FOR IMMEDIATE RELEASE

December 23, 1998

Lyme Disease Vaccine

 


FOR MORE INFORMATION

Contact Mary Landrigan

(914) 637-4715

The Westchester County Department of Health today announced the FDA approval of the first vaccine for Lyme disease. The new vaccine, LYMErix, is approved for use in people 15 to 70 years of age who live or work in grassy or wooded areas where infected ticks are present.

"The vaccine offers Westchester residents another defense against Lyme disease and will be available in January," stated Dr. Harold N. Adel, Westchester County Health Commissioner. "Residents considering the vaccine should consult with their physicians."

For maximum protection, three injections of the vaccine must be taken over a one year period. The injections are given at 0,1 and 12 months. After three shots the vaccine was shown to be 78% effective, after two shots 50% effective.

"Although this is a significant breakthrough, residents should not stop taking the standard precautions against tickborne diseases, such as wearing protective clothing and doing tick checks," Dr. Adel added. "The vaccine is not 100% effective and offers no protection against other tickborne diseases such as ehrlichiosis."

LYMErix contains a genetically engineered protein from an outer surface protein of Borrelia burgdorferi, the spiral shaped bacterium that is responsible for Lyme disease. The surface protein, called OspA, stimulates antibodies that appear to disable the bacterium's ability to infect the individual.

SmithKline Beecham, the manufacturer of the vaccine, is studying whether booster shots will be necessary. The company is also conducting a clinical trial on whether the vaccine is safe for children under 15 years of age. The vaccine is not recommended for use yet in children, pregnant women, those already with chronic Lyme disease, and those already with chronic arthritis. The vaccine also may interfere with testing for the diagnosis of Lyme disease.

Lyme disease is passed on to people through the bite of an infected deer tick. The most common symptom is an expanding red rash, often at the site of the tick bite. The rash usually appears three to 30 days after the bite and may last for weeks. Other symptoms may include fever, sore throat, fatigue, sleeping difficulties, stiff neck, joint and muscle pain, swollen glands and dizziness.

Ehrlichiosis is also spread through the bite of an infected deer tick. Symptoms of ehrlichiosis can include fever, headache, chills, malaise, muscle and joint pain, and nausea and vomiting. Acute weight loss, low platelet count, and low white blood cell count can also occur.

For more information on the Lyme disease vaccine, call the Westchester County Department of Health at (914) 813-5000. Information for the general public and physicians will be available shortly at the Westchester County Department of Health website www.co.westchester.ny.us/health.

 

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